Leishmaniasis: Pathogenesis and Potential Treatment
暫譯: 利什曼病：病理機制與潛在治療
Singh, Veer, Kumar, Ashish, Abhishek, Kumar
- 出版商: CRC
- 出版日期: 2026-07-06
- 售價: $4,970
- 貴賓價: 9.5 折 $4,721
- 語言: 英文
- 頁數: 316
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 1032979755
- ISBN-13: 9781032979755
尚未上市，無法訂購
商品描述
This book covers the history, biology, pathogenesis, clinical manifestations, and the latest advancements in diagnosis, treatment, and control strategies against leishmaniasis. Chapter 1 presents the life cycle of Leishmania parasites, focusing on vector biology and transmission dynamics, while elucidating the mechanisms of infection and disease progression. The clinical manifestations of cutaneous, visceral, and mucocutaneous leishmaniasis are examined in detail, alongside the immune response of the host and the evasion strategies by the parasite. It also investigates the genetic and molecular diversity of Leishmania, highlighting their virulence mechanisms, and reviews diagnostic methods from traditional techniques to advanced molecular diagnostics. The chapter also covers the current therapeutic approaches, including potential drugs and combination therapies along with integrated vector management strategies for effective disease control. The book explores preventive measures, community interventions, and public health strategies, addressing challenges in leishmaniasis research and identifying knowledge gaps. It presents real-world applications and outcomes through case studies and clinical trials. This book is useful for researchers and students of infectious diseases, tropical medicine, and parasitology.
Key Features:
- Explores the pathogenesis and epidemiology of leishmaniasis, providing a global perspective on its public health impact
- Details the life cycle of Leishmania parasites, focusing on vector biology, transmission dynamics, and mechanisms of infection
- Examines the clinical manifestations of cutaneous, visceral, and mucocutaneous leishmaniasis, including the host immune response and parasite evasion strategies
- Reviews current therapeutic approaches, including potential drugs, combination therapies, and integrated vector management strategies for effective control
- Presents preventive measures, community interventions, public health strategies, and the challenges in leishmaniasis research
商品描述(中文翻譯)
這本書涵蓋了利什曼病的歷史、生物學、發病機制、臨床表現，以及最新的診斷、治療和控制策略的進展。第一章介紹了Leishmania 寄生蟲的生活週期，重點關注媒介生物學和傳播動力學，同時闡明感染和疾病進展的機制。詳細檢視了皮膚型、內臟型和黏膜皮膚型利什曼病的臨床表現，並探討了宿主的免疫反應及寄生蟲的逃避策略。該章還研究了Leishmania 的遺傳和分子多樣性，突顯其致病機制，並回顧了從傳統技術到先進分子診斷的診斷方法。章節還涵蓋了當前的治療方法，包括潛在藥物和聯合療法，以及有效疾病控制的綜合媒介管理策略。這本書探討了預防措施、社區干預和公共衛生策略，解決了利什曼病研究中的挑戰並識別知識空白。通過案例研究和臨床試驗，展示了現實世界的應用和結果。本書對於傳染病、熱帶醫學和寄生蟲學的研究者和學生非常有用。
主要特點：
- 探討利什曼病的發病機制和流行病學，提供其公共衛生影響的全球視角
- 詳細介紹Leishmania 寄生蟲的生活週期，重點關注媒介生物學、傳播動力學和感染機制
- 檢視皮膚型、內臟型和黏膜皮膚型利什曼病的臨床表現，包括宿主免疫反應和寄生蟲逃避策略
- 回顧當前的治療方法，包括潛在藥物、聯合療法和有效控制的綜合媒介管理策略
- 提出預防措施、社區干預、公共衛生策略，以及利什曼病研究中的挑戰
作者簡介
Veer Singh is currently working as Young Scientist (DHR) at the Department of Biochemistry, Rajendra Memorial Research Institute of Medical Sciences, Patna, India. He got PhD from the Indian Institute of Technology (Banaras Hindu University), Varanasi. He has more than 50 publications and his area of work involved Environmental contamination & toxicity, the role of drinking water heavy metals contamination in visceral leishmaniasis (VL) & post-kala-azar dermal leishmaniasis (PKDL) development. He has also published 6 books and 5 patents related to his research field.
Dr. Ashish Kumar is currently working as Scientist-C and Head of Department at the Department of Biochemistry, Rajendra Memorial Research Institute of Medical Sciences, and Patna, India. He has published more than 45 publications in International/national journals. He has received several awards and received several funding (sponsored projects) from many national and international agencies. Currently, 4 doctoral and 2 postdoctoral students are working under the supervision of Dr. Ashish Kumar. Dr. Kumar is working in the interdisciplinary area of life science. His work is mainly focused on visceral leishmaniasis (VL) and post kala-azar dermal leishmaniasis (PKDL). He is also working on VL and PKDL diagnosis, treatment and environmental impacts on disease development.
Kumar Abhishek is currently working as Scientist-C, Department of Health Research, Model Rural Health Research Unit (MRHRU), Kurhani, Muzaffarpur, under ICMR- Rajendra Memorial Research Institute of Medical Sciences, Patna, (Bihar) India. He got his Ph.D. from the Department of Microbiology, University of Calcutta, West Bengal. He has more than 26 publications in peer reviewed journals. He works in the field of visceral leishmaniasis (VL), post-kala-azar dermal leishmaniasis (PKDL), parasitic diseases and on the epidemiology of communicable and non-communicable diseases.
作者簡介(中文翻譯)
維爾·辛格目前在印度巴特那的拉根德拉紀念醫學科學研究所生物化學系擔任青年科學家（DHR）。他在印度理工學院（班納拉斯印度大學）獲得博士學位。他擁有超過50篇的出版物，研究領域涉及環境污染與毒性、飲用水中重金屬污染在內臟利什曼病（VL）及後卡拉阿札皮膚利什曼病（PKDL）發展中的角色。他還出版了6本書籍和5項與其研究領域相關的專利。
阿希什·庫馬博士目前在印度巴特那的拉根德拉紀念醫學科學研究所生物化學系擔任科學家-C及系主任。他在國際/國內期刊上發表了超過45篇的出版物。他獲得了多項獎項，並從許多國內外機構獲得了多項資助（贊助項目）。目前，有4名博士生和2名博士後研究生在阿希什·庫馬博士的指導下工作。庫馬博士的研究領域為生命科學的跨學科領域，主要集中在內臟利什曼病（VL）和後卡拉阿札皮膚利什曼病（PKDL）。他還在進行VL和PKDL的診斷、治療以及環境對疾病發展的影響研究。
庫馬·阿比謝克目前在印度比哈爾邦穆扎法爾普爾的健康研究部門，模範鄉村健康研究單位（MRHRU）擔任科學家-C，隸屬於ICMR-拉根德拉紀念醫學科學研究所。他在西孟加拉的加爾各答大學微生物學系獲得博士學位。他在同行評審的期刊上發表了超過26篇的出版物。他的研究領域包括內臟利什曼病（VL）、後卡拉阿札皮膚利什曼病（PKDL）、寄生蟲疾病以及傳染病和非傳染病的流行病學。
