Cell-Free Macromolecular Synthesis
暫譯: 無細胞大分子合成

Lu, Yuan, Jewett, Michael C.

Cell-Free Macromolecular Synthesis
  • 出版商: Springer
  • 出版日期: 2025-04-02
  • 售價: $10,350
  • 貴賓價: 9.5 折 $9,833
  • 語言: 英文
  • 頁數: 146
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3031412893
  • ISBN-13: 9783031412899
  • 相關分類: 生物資訊 Bioinformatics

    • 海外代購書籍(需單獨結帳)

相關主題

商品描述

This book reviews cell-free production systems, exploring the frontiers in cellular engineering and biotechnology. With contributions from experts in the field, the book offers a comprehensive and up-to-date account of the latest advancements and practical applications. The volume covers a diverse range of topics, beginning with an in-depth analysis of cell-free display techniques for protein evolution, shedding light on the methodologies used to engineer proteins for diverse purposes, followed by an examination of bottom-up synthetic biology employing cell-free protein synthesis. Additionally, it investigates the intricacies of the cell-free synthesis of metalloproteins, elucidating the unique properties and functionalities of these biologically important molecules.

In this book, particular attention is given to the integration of cell-free production systems with droplet microfluidics, a pioneering approach that has revolutionized research activities in both academic and industrial settings. Readers will also discover the latest advancements in cell-free protein synthesis and immobilization, and find out more about the eCell technology, which combines cell-free protein synthesis with bio-sensing and remediation, revolutionizing critical areas of study in biotechnology.

Together with the companion volume entitled "Cell-free Production: System Development", both books highlight the research progresses on the basic and applied research of cell-free production systems in the last few years, and are invaluable resources for scholars, researchers, and bioengineers. This book also appeals to enthusiasts of synthetic biology.

商品描述(中文翻譯)

本書回顧了無細胞生產系統，探索了細胞工程和生物技術的前沿。書中匯集了該領域的專家貢獻，提供了最新進展和實際應用的全面且最新的報導。本書涵蓋了多樣的主題，首先深入分析了用於蛋白質演化的無細胞顯示技術，闡明了用於多種目的的蛋白質工程方法，接著探討了採用無細胞蛋白質合成的自下而上的合成生物學。此外，本書還研究了金屬蛋白的無細胞合成的複雜性，闡明了這些生物重要分子的獨特性質和功能。

本書特別關注無細胞生產系統與液滴微流體技術的整合，這是一種革命性的先進方法，徹底改變了學術界和工業界的研究活動。讀者還將發現無細胞蛋白質合成和固定化的最新進展，並了解 eCell 技術，該技術將無細胞蛋白質合成與生物感測和修復相結合，徹底改變了生物技術中的關鍵研究領域。

與名為《無細胞生產：系統開發》的伴隨卷一起，這兩本書突顯了近幾年來無細胞生產系統的基礎和應用研究的進展，對學者、研究人員和生物工程師來說都是寶貴的資源。本書同樣吸引合成生物學的愛好者。

作者簡介

Yuan Lu is an Associate Professor at the Department of Chemical Engineering, Tsinghua University, China. After receiving B.S. (2004) and Ph.D. (2009) in chemical engineering from Tsinghua University, China, Dr Lu received postdoctoral training from Johns Hopkins University (2009-2010) and Stanford University (2010-2014), USA. He was a project researcher from 2014 to 2016 at the University of Tokyo, Japan. The central paradigm of Dr Lu's research is using interdisciplinary approaches in engineering, biology, chemistry, physics, and computer science to manipulate biomolecules and complex biological systems. The main focus lies on developing and applying synthetic biology and other cutting-edge technologies to engineer nucleic acids, proteins, pathways, and networks for addressing most daunting challenges in human health.

Michael Jewett Michael Jewett is a Professor of Bioengineering at Stanford University. Dr. Jewett received his PhD in 2005 at Stanford University, completed postdoctoral studies at the Center for Microbial Biotechnology in Denmark and the Harvard Medical School, and was a guest professor at the Swiss Federal Institute of Technology (ETH Zurich). He is the recipient of the NIH Pathway to Independence Award, David and Lucile Packard Fellowship in Science and Engineering, Camille-Dreyfus Teacher-Scholar Award, and a Finalist for the Blavatnik National Awards for Young Scientists, among others. He is the co-founder of SwiftScale Biologics, Stemloop, Inc., Pearl Bio, Design Pharmaceuticals, and Gauntlet Bio. Jewett is a Fellow of AIMBE, AAAS, and NAI.

Jewett's lab focuses on advancing synthetic biology research in support of planet and societal health. The key idea is to make biology easier to engineer. They develop data-driven, multiplexed methods to elucidate fundamental principles about how the living world works and use knowledge from these insights to create cell-free biotechnologies for transforming bioengineering applications in health, manufacturing, sustainability, and education.

作者簡介(中文翻譯)

盧元是中國清華大學化學工程系的副教授。盧博士於2004年和2009年在清華大學獲得化學工程學士和博士學位，隨後在美國約翰霍普金斯大學（2009-2010）和史丹佛大學（2010-2014）接受博士後訓練。他於2014年至2016年在日本東京大學擔任專案研究員。盧博士的研究核心範式是利用工程學、生物學、化學、物理學和計算機科學的跨學科方法來操控生物分子和複雜的生物系統。主要重點在於開發和應用合成生物學及其他尖端技術，以工程化核酸、蛋白質、途徑和網絡，解決人類健康面臨的最艱鉅挑戰。

邁克爾·朱維特是史丹佛大學的生物工程教授。朱維特博士於2005年在史丹佛大學獲得博士學位，並在丹麥微生物生物技術中心和哈佛醫學院完成博士後研究，還曾擔任瑞士聯邦理工學院（ETH Zurich）的客座教授。他是美國國立衛生研究院（NIH）獨立之路獎、戴維與露西爾·帕卡德科學與工程獎學金、卡蜜爾·德雷福斯教師學者獎以及布拉瓦特尼克全國青年科學家獎的決賽入圍者等多項獎項的獲得者。他是SwiftScale Biologics、Stemloop, Inc.、Pearl Bio、Design Pharmaceuticals和Gauntlet Bio的共同創辦人。朱維特是美國醫學與生物工程學會（AIMBE）、美國科學促進會（AAAS）和國家發明家學院（NAI）的院士。

朱維特的實驗室專注於推進合成生物學研究，以支持地球和社會健康。其關鍵理念是使生物學的工程化變得更容易。他們開發數據驅動的多重方法，以闡明有關生命世界運作的基本原則，並利用這些見解所獲得的知識創造無細胞生物技術，轉變健康、製造、可持續性和教育等領域的生物工程應用。

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