Multi-Dimensional Vibrational Circular Dichroism

Sato, Hisako, Yoshida, Jun, Yamagishi, Akihiko

Multi-Dimensional Vibrational Circular Dichroism
  • 出版商: Springer
  • 出版日期: 2024-03-30
  • 售價: $6,500
  • 貴賓價: 9.5 折 $6,175
  • 語言: 英文
  • 頁數: 209
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 9819703905
  • ISBN-13: 9789819703906

    • 海外代購書籍(需單獨結帳)

商品描述

This book provides the reader with the latest research on vibrational circular dichroism (VCD) spectroscopy including its useful features and applications to many fields. The book starts from an unresolved question in gel chemistry of how component molecules are organized in the flexible fibrils of gels. VCD spectroscopy was successful in giving a clear answer to this mystery. The book also describes a key aspect of this technique lay in the fact that VCD signals were remarkably enhanced when chiral molecules formed a stereoregular molecular array over a few hundred nanometers. VCD spectroscopy was also applied to other topics involving chiral molecules such as the chiral discrimination mechanism in heterogeneous asymmetric catalysis and the build-up of supramolecular chirality in molecular crystals. Furthermore, the book covers the recent instrument developments leading to multi-dimensional VCD measurements with the coordinates of wavenumber, space and time. This progress has opened up new biological and medical applications such as the heterogenous distributions of protein domains in insect wings and the quality control of chiral drugs. The last part of the book presents the possibility of medical diagnosis of Alzheimer's disease through multi-dimensional VCD analyses.

This book appeals not only to researchers and students who study spectroscopy but also to ones in catalysis, biology and medicine as users of the VCD methods.


商品描述(中文翻譯)

本書提供讀者關於振動圓二色性（VCD）光譜學的最新研究，包括其有用的特點和在許多領域的應用。本書從凝膠化學中一個未解決的問題開始，即在凝膠的柔性纖維中，組分分子是如何組織起來的。VCD光譜學成功地解答了這個謎團。本書還描述了這項技術的一個關鍵方面，即當手性分子形成幾百納米的立體規則分子排列時，VCD信號顯著增強。VCD光譜學還應用於涉及手性分子的其他主題，如非均相不對稱催化中的手性辨識機制和分子晶體中超分子手性的建立。此外，本書還介紹了最近的儀器發展，實現了具有波數、空間和時間坐標的多維VCD測量。這一進展開拓了生物和醫學應用的新可能性，例如昆蟲翅膀中蛋白質區域的非均勻分佈和手性藥物的質量控制。本書的最後一部分介紹了通過多維VCD分析可能對阿爾茨海默病進行醫學診斷的可能性。

本書不僅吸引了研究光譜學的研究人員和學生，也吸引了催化、生物學和醫學領域的使用VCD方法的人士。

作者簡介

Hisako Sato received the Dr. Sci. degree from Hokkaido University, Hokkaido, Japan, in 1992 and the Dr. Eng. degree from the University of Tokyo, Tokyo, Japan, in 1999. In 1983, she joined Hitachi, Ltd., Tokyo, Japan. She moved to the University of Tokyo as a research fellow in 2002. From 2003 to 2006, she was a CREST researcher by JST. She was a PRESTO project leader by JST from 2006 to 2010. In 2009, she joined Ehime University as an associate professor in the Graduate School of Science and Engineering. During 2010-2022, she was a full professor at Ehime University. She retired Ehime University at the end of March in 2023. She is researcher in Ehime University from 2023. Her current interest is the application of the solid-state VCD and time-step VCD methods to unravel the dynamic aspects of chiral molecular aggregates or inorganic layered materials or biological organs.

Jun Yoshida received the Dr. Sci. degree from the University of Tokyo in 2009.After working at Kao Corporation, he joined Kitasato University as an assistant professor and later as a lecturer. During 2014-2015, he stayed at Simon Fraser University as a visiting researcher. In 2021, he moved to Nihon University as an associate professor. His current interest is the development of helical supramolecules and understanding the inner structure.

Akihiko Yamagishi received the Dr. Sci. degree from the University of Tokyo, Tokyo, Japan, in 1975. He was a professor in the Graduate School of Science at the University of Tokyo during 2001-2005. He is a visiting researcher in the Department of Medicine at Toho University. He received the Award for Creative Work from the Chemical Society of Japan in 1986, the Award from the Clay Mineral Society of Japan in 1999 and the Marilyn and Sturges W. Bailey Distinguished Member Award from the American Clay Mineral Society in 2012. He is a fellow of the Chemical Society of Japan.

作者簡介(中文翻譯)

Hisako Sato於1992年在日本北海道大學獲得博士學位，並於1999年在日本東京大學獲得工學博士學位。1983年，她加入了日本東京的日立公司。2002年，她轉到東京大學擔任研究員。2003年至2006年期間，她擔任日本科學技術振興機構的CREST研究員。2006年至2010年期間，她擔任日本科學技術振興機構的PRESTO項目負責人。2009年，她加入愛媛大學工學研究科擔任副教授。2010年至2022年期間，她在愛媛大學擔任教授。她於2023年3月底退休，並從2023年起成為愛媛大學的研究員。她目前的研究興趣是應用固態VCD和時間步長VCD方法來揭示手性分子聚集體、無機層狀材料或生物器官的動態特性。

Jun Yoshida於2009年在東京大學獲得博士學位。在加入花王公司工作後，他擔任北里大學的助理教授和講師。2014年至2015年期間，他在西蒙菲莎大學擔任訪問研究員。2021年，他轉到日本大學擔任副教授。他目前的研究興趣是開發螺旋超分子並理解其內部結構。

Akihiko Yamagishi於1975年在東京大學獲得博士學位。他曾在東京大學理學研究科擔任教授（2001年至2005年）。他是東邦大學醫學系的訪問研究員。他於1986年獲得日本化學學會的創新工作獎，1999年獲得日本黏土礦物學會的獎項，並於2012年獲得美國黏土礦物學會的Marilyn和Sturges W. Bailey傑出會員獎。他是日本化學學會的會士。

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